10 bestAntihistamineof May 2025
112M consumers helped this year.
24% off
1
Allevia Hayfever Allergy Tablets, Prescription Strength 120mg Fexofenadine, 24hr Relief Acts Within 1 Hour, Including Sneezing, Watery Eyes, Itchy & Runny Nose, 30 Tablets
Allevia
9.7
40% off
2
6 Months Supply Loratadine Hayfever & Allergy Relief 10mg Tablets (30x6) GSL
BESTOPE PRO
9.4
39% off
3
Clarityn Allergy Relief Tablet | Hayfever Relief Tablet | Loratadine | Antihistamine | All day maximum strength symptom relief with one tablet per day | 30 count (pack of 1)
Clarityn
9.1
8% off
4
Galpharm Treathay Hayfever Relief Fexofenadine, 30 Count (Pack of 1)
Galpharm
8.8
32% off
5
6 Months Supply Cetirizine Hayfever Allergy Tablets 30 x 6
6 Months Supply Cetirizine Hayfever Allergy Tablets 30 x 6
8.6
OtherUp to 40% off
Benadryl Allergy Relief Capsules (1 x 12 Capsules), Antihistamine Capsules with Acrivastine, Hayfever Capsules for Allergy Relief from Hay Fever Symptoms, Suitable for Pet, Dust, and Skin Allergies
Allergy Relief Tablets - Fast Acting Antihistamine for Hayfever, Pet, Dust, and Skin Allergies - Treatment for Itchiness, Redness, Swelling & Irritation - 84 Tablets
240 x 10mg Cetirizine Dihydrochloride (8 Months Supply) One a Day hay Fever and Allergy Relief Tablets (8x30 Tablets)
Piriteze Hayfever & Allergy Antihistamine Tablets, Allergy Relief, Cetirizine, 7s
6
Piriteze Tablets, 30s
PIRITEZE
8.3
26% off
7
Benadryl Allergy One A Day 10 Mg Tablets - Effective and Long-Lasting Relief from Hay Fever, Pet, Skin and Dust Allergies - 30 Count
Benadryl
8.0
16% off
8
Histallay Hayfever & Allergy Relief Tablets, 30 Tablets, 120mg Fexofenadine, Antihistamine 24hr Relief, Acts Within 1hr, Relieves Hayfever, Pet, Dust and Mould Allergies
HISTALLAY
7.7
9
6 Months Supply Allacan Cetirizine Hayfever Allergy Tablets 30 x 6
Allacan
7.4
10
Allevia Allergy Tablets | 70 Tablets | 120mg Fexofenadine | 24hr Relief Acts within 1 Hour | Non-drowsy in Most People | Relieves Hayfever, Pet, Dust and Mould Allergies
Allevia
7.1
A Guide to Selecting the Best Antihistamine
When choosing an antihistamine, it's important to consider your specific needs and how the medication will fit into your lifestyle. Antihistamines are used to relieve symptoms of allergies, such as sneezing, itching, and runny nose. They work by blocking the action of histamine, a substance in the body that causes allergic symptoms. There are different types of antihistamines, and they can vary in terms of how quickly they work, how long they last, and their potential side effects. Understanding these differences can help you choose the right antihistamine for your situation.
Type of Antihistamine
Antihistamines are generally divided into two categories: first-generation and second-generation. First-generation antihistamines are older and can cause drowsiness, which might be beneficial if you need help sleeping but could be a drawback if you need to stay alert. Second-generation antihistamines are newer and are less likely to cause drowsiness, making them a better choice for daytime use. Consider when you plan to take the medication and whether drowsiness would be a problem for you.
Onset of Action
This refers to how quickly the antihistamine begins to work after you take it. Some antihistamines start working within 30 minutes, while others may take a few hours. If you need quick relief from allergy symptoms, look for an antihistamine with a fast onset of action. If your symptoms are more predictable, such as seasonal allergies, a slower onset might be acceptable.
Duration of Effect
This is how long the antihistamine continues to work after taking it. Some antihistamines provide relief for only a few hours, while others can last up to 24 hours. If you need all-day relief, a longer-lasting antihistamine might be more convenient, as it reduces the need for multiple doses throughout the day.
Side Effects
Different antihistamines can have different side effects. Common side effects include drowsiness, dry mouth, and dizziness. If you are sensitive to these effects or need to avoid them for specific activities, such as driving, you may want to choose a second-generation antihistamine, which typically has fewer side effects. Always consider how the side effects might impact your daily activities.
Formulation
Antihistamines come in various forms, including tablets, capsules, liquids, and nasal sprays. The choice of formulation can depend on personal preference and convenience. For example, if you have difficulty swallowing pills, a liquid or chewable tablet might be preferable. Nasal sprays can be effective for targeting nasal symptoms directly. Consider which form you are most comfortable using and which fits best into your routine.
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