10 bestToothache Relieverof January 2026
112M consumers helped this year.
1

Orajel Dental Gel for Rapid Toothpain Relief - Benzocaine 10% w/w, Fast-Acting Dental Pain Relief Formula, 5.3g
Orajel

9.8
2

Nurofen Express Ibuprofen Tablets, 256mg, 16 Tablets, Painkillers, Sinus Relief, Migraine Relief, Headache Relief, Tooth Pain Relief, Toothache, Flu Tablets, Long Lasting, Cold and Flu
Nurofen

9.6
3

Deluxe Dentals Fast Acting Pure Botanical Oils Remedy for Teeth and Gums, Gum Disease Treatment for Adults, Toothache Treatment Clove Oil for Toothache,
Deluxe Dentals

9.4
21% off
4

Anbesol Adult Strength Gel for Effective Oral Pain Relief from Mouth Ulcers and Denture Irritation, 10g
Anbesol

9.2
5

Apiprodent Spray - Helps Protect and Recovery of Damages Gums and Oral Cavity – Relief from Sore Gums, Gum Sensitivity and Bleeding Gums- 20 ml bottle
apipharma

8.9
OtherUp to 20% off
6

NPOW Clove Oil for Toothache Pain Relief for Adult – Oil of Cloves for Toothache Natural Dental Solution, Clove Essential Oil, Clove Extract for Oral Care, Tooth Pain Relief and Dental Health - 10ml
NPOW

8.7
10% off
7

IB Gum Disease Treatment Oil for Gingivitis, Bad Breath & Oral Pain 15 ml
Infinitive Beauty

8.4
6% off
8

2 x Orajel Dental Gel Rapid Toothache Relief Benzocaine 10% w/w (2 Packs)
Orajel

8.1
9

Orasore Dental Gel 10gms - with Clove for Soothing Rapid Toothache Relief and Dental Cavity
CloudBazaar 247

7.8
10

Nurofen Express Ibuprofen Tablets, 16 Pain Relief Caplets, Dental Pain Relief, Tooth Pain Relief, Toothache, Wisdom Tooth Pain Relief, Targets Pain Fast, Cold and Flu, Over-The-Counter Medication
Nurofen

7.6
A Guide to Selecting the Best Toothache Reliever
When choosing a toothache reliever, it's important to consider the type of pain you're experiencing, the cause of the toothache, and any personal preferences or sensitivities you may have. Toothache relievers come in various forms, including topical gels, oral medications, and natural remedies. Understanding the key specifications of each option will help you make an informed decision that best suits your needs and provides effective relief.
Type of Reliever
Toothache relievers can be categorized into topical gels, oral medications, and natural remedies. Topical gels are applied directly to the affected area and provide localized pain relief. Oral medications, such as over-the-counter painkillers, work systemically to reduce pain and inflammation. Natural remedies, like clove oil or saltwater rinses, offer a more holistic approach. Consider the severity of your pain and your preference for natural versus pharmaceutical solutions when choosing the type of reliever.
Active Ingredients
The active ingredients in toothache relievers are crucial as they determine the effectiveness of the product. Common active ingredients include benzocaine in topical gels, which numbs the area, and ibuprofen or acetaminophen in oral medications, which reduce pain and inflammation. If you have allergies or sensitivities, it's important to check the active ingredients to avoid adverse reactions. Choose an active ingredient that aligns with your pain relief needs and any medical advice you have received.
Duration of Relief
The duration of relief provided by a toothache reliever can vary significantly. Some products offer quick but short-term relief, while others provide longer-lasting effects. Topical gels may offer immediate relief but need frequent reapplication, whereas oral medications might take longer to kick in but last several hours. Consider how long you need relief and how often you're willing to reapply or take the medication when selecting a product.
Ease of Use
Ease of use is an important factor, especially if you're in significant pain. Topical gels can be messy and require precise application, while oral medications are generally straightforward to take. Natural remedies might require preparation, such as diluting essential oils or mixing a saltwater rinse. Consider your comfort level with applying or taking the product and choose one that fits your lifestyle and pain management routine.
Side Effects
All toothache relievers come with potential side effects, which can range from mild to severe. Topical gels may cause temporary numbness or irritation, while oral medications can lead to stomach upset or allergic reactions. Natural remedies are generally considered safer but can still cause reactions in sensitive individuals. It's important to weigh the potential side effects against the benefits of pain relief and choose a product that minimizes risk while effectively managing your toothache.
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