10 bestAntihistamines For Dogsof May 2025
112M consumers helped this year.
1

YuMOVE Skin & Coat Care Itching for Adult Dogs | Previously YuDERM Itching Dog | Itchy or Sensitive Skin Supplement for Dogs Prone to Scratching enriched with Salmon Oil | 250ml | Packaging may vary
Yumove

9.9
2

RenaSan Animal First Aid Spray (100ml) – Fights infection, kills bacteria & stops itching, Veterinary-grade skin protection, Alcohol-Free, Non-irritating, for Dogs, Cats & all other animals.
RenaSan

9.8
30% off
3

6 Months Supply Cetirizine Hayfever Allergy Tablets 30 x 6
Bizzico

9.7
34% off
4

6 Months Supply Loratadine Hayfever & Allergy Relief 10mg Tablets (30x6) GSL
BESTOPE PRO

9.6
18% off
5

Clarityn Allergy Relief Tablet | Hayfever Relief Tablet | Loratadine | Antihistamine | All day maximum strength symptom relief with one tablet per day | 30 count (pack of 1)
Clarityn

9.4
OtherUp to 15% off
11% off
6

Leucillin Natural Antiseptic Spray - Antibacterial Antifungal Antiviral for Dogs Cats All Animals Itchy Skin Minor Wound Care and Skin Health | 250ml
Leucillin

9.2
20% off
7

ZyranovaE Dog Allergy Relief Chews(Peking Duck Flavor 150 Count)- Allergy Relief immune Chews,Hot Spot for Dogs,Dog Itch Relief,Anti Itch for Dogs,Itchy Skin,Seasonal Allergies
ZyranovaE

8.9
8

Benadryl Allergy One A Day 10 Mg Tablets - Effective and Long-Lasting Relief from Hay Fever, Pet, Skin and Dust Allergies - 30 Count
Benadryl

8.7
27% off
9

6 Months Supply Allacan Cetirizine Hayfever Allergy Tablets 30 x 6
NECALON

8.5
11% off
10

Benadryl Allergy Relief Capsules (1 x 24 Capsules), Antihistamine Capsules with Acrivastine, Hayfever Capsules for Allergy Relief from Hay Fever Symptoms, Suitable for Pet, Dust, and Skin Allergies
Benadryl

8.2
A Guide to Selecting the Best Antihistamines For Dogs
Choosing the right antihistamine for your dog can be a crucial step in managing allergies and ensuring their comfort. Antihistamines help to alleviate symptoms such as itching, sneezing, and runny eyes caused by allergic reactions. When selecting an antihistamine, it's important to consider several key factors to ensure it meets your dog's specific needs. Here are some important specifications to consider and how to navigate them.
Active Ingredient
The active ingredient in an antihistamine is the component that works to block histamines and reduce allergy symptoms. Common active ingredients include diphenhydramine, cetirizine, and loratadine. Each ingredient may work differently and have varying effectiveness for different types of allergies. It's important to consult with your veterinarian to determine which active ingredient is best suited for your dog's specific allergy type and severity.
Dosage Form
Antihistamines for dogs come in various dosage forms such as tablets, capsules, liquid, and chewable treats. The form you choose can depend on your dog's preferences and ease of administration. For example, if your dog is picky or has difficulty swallowing pills, a liquid or chewable form might be more suitable. Consider your dog's behavior and preferences when selecting the dosage form to ensure they receive the medication without stress.
Dosage Strength
Dosage strength refers to the amount of active ingredient in each dose of the antihistamine. This is important because it determines how much of the medication your dog will receive. Dosage strength can vary widely, and it's crucial to follow your veterinarian's recommendations to avoid underdosing or overdosing. The right dosage strength will depend on your dog's weight, age, and the severity of their allergies.
Side Effects
All medications can have side effects, and antihistamines are no exception. Common side effects in dogs may include drowsiness, dry mouth, and urinary retention. It's important to be aware of potential side effects and monitor your dog after administering the medication. If your dog experiences severe or unexpected side effects, contact your veterinarian immediately. Understanding the side effects can help you make an informed decision and ensure your dog's safety.
Duration of Action
Duration of action refers to how long the antihistamine remains effective in your dog's system. Some antihistamines provide relief for a few hours, while others can last up to 24 hours. Depending on your dog's needs and the severity of their allergies, you may prefer a longer-acting antihistamine to reduce the frequency of dosing. Consider your dog's daily routine and how often you can administer the medication when choosing the duration of action.
Veterinary Approval
Not all antihistamines are safe for dogs, and some human medications can be harmful. It's essential to choose an antihistamine that is specifically approved for veterinary use. Consult your veterinarian before giving any medication to your dog to ensure it is safe and appropriate for their condition. Veterinary approval ensures that the antihistamine has been tested and deemed safe for canine use.

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