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9 bestCold Sore Creamsof May 2025

112M consumers helped this year.

14% off

1

Herstat Effective Propolis Ointment - Cold Sores
Herstat Effective Propolis Ointment - Cold Sores

Herstat

9.9

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2

LYSINE Lip Balm 2 Tube Saver Pack 0.15 OZ (4 g) Fast Dispatch 312
LYSINE Lip Balm 2 Tube Saver Pack 0.15 OZ (4 g) Fast Dispatch 312

P.R.

9.8

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10% off

3

Cymex Cream for Cold Sores x 2
Cymex Cream for Cold Sores x 2

Cymex

9.8

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7% off

4

Bonjela 15g Oral Gel - Fast Acting Pain Relief For Mouth Ulcers, Cold Sores, Swelling, Infection, Suitable With Dentures, Adult Treatment, Quick Medication Solution
Bonjela 15g Oral Gel - Fast Acting Pain Relief For Mouth Ulcers, Cold Sores, Swelling, Infection, Suitable With Dentures, Adult Treatment, Quick Medication Solution

Bonjela

9.7

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5

Compeed Cold Sore Discreet Healing Patch, 45 Patches (3 Packs of 15), Cold Sore Treatment, More Convenient than Cold Sore Creams, Dimensions: 1.5 x 1.5 cm
Compeed Cold Sore Discreet Healing Patch, 45 Patches (3 Packs of 15), Cold Sore Treatment, More Convenient than Cold Sore Creams, Dimensions: 1.5 x 1.5 cm

Compeed

9.5

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6

Galpharm Cold Sore Cream 2g x 3 Packs
Galpharm Cold Sore Cream 2g x 3 Packs

Galpharm

9.4

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18% off

7

5 x Cold Sore Treatment - 2g Cream - 5% w/w (5 x Lipsore Cream)
5 x Cold Sore Treatment - 2g Cream - 5% w/w (5 x Lipsore Cream)

Lipsore

9.2

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5% off

8

Zovirax Cold Sore Relief Treatment Cream Pump 5% - 2g Pump
Zovirax Cold Sore Relief Treatment Cream Pump 5% - 2g Pump

Fixbub

8.9

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10% off

9

Hubner Silicea Cold Sore Gel
Hubner Silicea Cold Sore Gel

Anton Hubner

8.7

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A Guide to Selecting the Best Cold Sore Creams

Choosing the right cold sore cream can make a significant difference in how quickly and effectively you can manage and heal cold sores. Cold sores, caused by the herpes simplex virus, can be painful and unsightly, so it's important to select a cream that suits your needs and provides the best relief. Here are some key specifications to consider when picking a cold sore cream, along with explanations to help you make an informed decision.

Active Ingredients

The active ingredients in a cold sore cream are crucial because they determine the cream's effectiveness in treating the virus and alleviating symptoms. Common active ingredients include antiviral agents like acyclovir or docosanol, which help to reduce the duration and severity of the outbreak. When choosing a cream, consider whether you need a strong antiviral treatment or if a milder, more soothing option is sufficient for your symptoms. If you experience frequent or severe outbreaks, a cream with a potent antiviral ingredient may be the best choice.

Application Frequency

How often you need to apply the cream can impact its convenience and effectiveness. Some creams require application every few hours, while others may only need to be applied a couple of times a day. If you have a busy lifestyle, you might prefer a cream that requires less frequent application. However, if you are able to apply the cream more regularly, a product that needs frequent application might provide faster relief.

Formulation

Cold sore creams come in various formulations, including gels, ointments, and creams. The formulation can affect how the product feels on your skin and how well it stays in place. Gels and ointments tend to be more occlusive, which can help protect the sore and keep the active ingredients in contact with the affected area. Creams are often lighter and may be more comfortable for some users. Consider your personal preference and how the product feels on your skin when choosing a formulation.

Additional Ingredients

Some cold sore creams contain additional ingredients that can provide extra benefits, such as moisturizers, pain relievers, or ingredients that promote healing. For example, creams with aloe vera or vitamin E can help soothe and hydrate the skin, while those with lidocaine or benzocaine can provide pain relief. If you have sensitive skin or specific needs, look for a cream with additional ingredients that address those concerns.

Onset of Action

The onset of action refers to how quickly the cream starts to work after application. Some creams may provide immediate relief from symptoms like pain and itching, while others might take longer to show results. If you need fast relief, look for a cream that is known for its quick onset of action. However, if you are more focused on long-term healing, the speed of relief might be less critical.

User Reviews

Reading user reviews can provide valuable insights into how well a cold sore cream works for others with similar symptoms. Reviews can highlight the effectiveness, ease of use, and any potential side effects of the product. While individual experiences can vary, looking at overall trends in reviews can help you gauge whether a particular cream is likely to meet your needs. Pay attention to reviews from users who have similar skin types or cold sore patterns to yours.

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